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नाक के पोलिप्स की सर्जरी और एस्परगिलस के इलाज के बाद लगातार नाक से पानी बहना और थकान होने पर क्या करें?
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Infectious Illnesses
Question #29111
74 days ago
180

नाक के पोलिप्स की सर्जरी और एस्परगिलस के इलाज के बाद लगातार नाक से पानी बहना और थकान होने पर क्या करें?

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जनवरी 2025 में जब मैं 32 साल का था, मैंने मेक्सिको में स्टेज 4 ऑब्सट्रक्टिव नेजल पॉलिप्स और फ्रंटल, एथमोइडल, स्फेनोइडल साइनस में मौजूद एस्परगिलस फ्यूमिगेटस के लिए सर्जरी करवाई थी। फंगस मेरे दिमाग से 1/2 मिलीमीटर दूर था और मेरे दिमाग को अंदर की ओर धकेल रहा था। इसने मेरे दिमाग के ड्यूरामेटर को सूजन देना शुरू कर दिया था। यह मेरी ऑप्टिक नर्व्स से 1/2 सेमी या उससे कम दूरी पर था। सर्जरी के बाद मुझे बताया गया कि फंगस का आकार एक मुट्ठी जितना था जब इसे एक साथ क्लंप किया गया। सर्जरी के बाद मैं 20 सालों में जितना अच्छा महसूस कर रहा था, उससे बेहतर महसूस कर रहा था। जब से मैं 13 साल का था, मुझे अस्पष्ट लेकिन गंभीर क्रॉनिक स्वास्थ्य समस्याएं थीं, जिनमें गंभीर थकान, हल्का बुखार, रात को पसीना आना, घुमते हुए दर्द और पीड़ा शामिल थे। सर्जरी के बाद मैं बहुत अच्छा महसूस कर रहा था, सिवाय थकान, रात को पसीना और कुछ जारी नेजल "एलर्जी" या नेजल डिस्चार्ज के। फिर सितंबर 2025 में मैंने फिर से बुरा महसूस करना शुरू किया: गंभीर सिरदर्द, साइनस कंजेशन, और अधिक थकान। मेरे न्यूरोसर्जन जो मेक्सिको में हैं, ने मुझसे फोन पर बात की और मुझे एंटीबायोटिक लेने की सलाह दी, अगर मुझे बैक्टीरियल इंफेक्शन हो रहा हो। मैंने इसे लिया, लेकिन कोई वास्तविक सुधार महसूस नहीं हुआ। फिर उन्होंने मुझे इट्राकोनाजोल लेने की सलाह दी, क्योंकि वह चिंतित थे कि मुझे एस्परगिलस फ्यूमिगेटस मेरे दिमाग में हो सकता है क्योंकि मेरी साइनस सर्जरी के बाद मेरा दिमाग अब एक्सपोज्ड है (एंडोस्कोप से आप मेरे पॉलिप्स छोटे होने पर ड्यूरामेटर देख सकते हैं)। जनवरी 2026 में मैं मेक्सिको यात्रा करने में सक्षम था। वहां मुझे मेरे ईएनटी ने बताया कि मेरे स्टेज 2 नेजल पॉलिप्स बढ़ गए हैं, कि मुझे बैक्टीरियल इंफेक्शन है, और मेरे खून में एस्परगिलस फ्यूमिगेटस के उच्च स्तर हैं। उच्च आईजीजी, आईजीएम, और आईजीई। मुझे मेरे ईएनटी द्वारा ओरल स्टेरॉयड्स, स्टेरॉयड स्प्रे, एंटीबायोटिक्स दिए गए। मेरे न्यूरोसर्जन ने मुझे एस्परगिलस के उच्च स्तर के कारण 2 महीने का इट्राकोनाजोल दिया। दोनों डॉक्टरों ने मुझे बताया कि मेरे घर में शायद एस्परगिलस फ्यूमिगेटस है और यह मेरे लिए अस्वस्थ वातावरण है। शुरू में मैंने बहुत बेहतर महसूस किया। मैंने लगभग 1 महीना मेक्सिको में बिताया। मुझे कभी भी चमकीला पीला स्राव और थकान नहीं रुकी, लेकिन मैं काफी अच्छा महसूस कर रहा था। जब मैं घर आया तो जल्द ही मैंने फिर से बुरा महसूस करना शुरू कर दिया। बहुत थका हुआ! अब मेरे नाक से ब्राउन चीज़ जैसे दानेदार बॉल्स निकल रहे हैं, साथ ही चमकीला पीला स्राव और काफी बार खून। कभी-कभी मैं जागता हूं और बलगम या जो भी हो, उसे निगलने और घुटने लगता हूं। कभी-कभी मैं सूंघता हूं और दानेदार बनावट वाला बलगम मेरे गले में चला जाता है। मुझे लगभग 100% यकीन है कि यह फंगस है। लेकिन मैं अपने घर से नहीं जा सकता क्योंकि मैं अपने माता-पिता के साथ रहता हूं और वे अपने आदर्श घर का खर्च नहीं उठा सकते, और मुझे नहीं लगता कि इट्राकोनाजोल मदद कर रहा है। या क्या मुझे इसे हर समय इस्तेमाल करते रहना होगा? मैं अभी डॉक्टर के पास जाने का खर्च नहीं उठा सकता।

How long have you been experiencing your current symptoms?:

- 1-3 months

How would you describe the severity of your fatigue?:

- Moderate — affects some activities

Have you noticed any specific triggers that worsen your symptoms?:

- Environmental factors (dust, mold)

How often do you experience nasal discharge or mucus?:

- Constantly

Have you had any other symptoms accompanying the nasal issues?:

- Nothing else

Have you made any changes in your home environment since your surgery?:

- Yes, major changes

Have you previously used itraconazole for an extended period?:

- Yes, for a longer duration
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Doctors' responses

Dr. Shayeque Reza
I completed my medical degree in 2023, but honestly, my journey in healthcare started way before that. Since 2018, I’ve been actively involved in clinical practice—getting hands-on exposure across multiple departments like ENT, pediatrics, dermatology, ophthalmology, medicine, and emergency care. One of the most intense and defining phases of my training was working at a District Government Hospital for a full year during the COVID pandemic. It was chaotic, unpredictable, and exhausting—but it also grounded me in real-world medicine like no textbook ever could. Over time, I’ve worked in both OPD and IPD setups, handling everything from mild viral fevers to more stubborn, long-term conditions. These day-to-day experiences really built my base and taught me how to stay calm when things get hectic—and how to adjust fast when plans don’t go as expected. What I’ve learned most is that care isn't only about writing the right medicine. It’s about being fully there, listening properly, and making sure the person feels seen—not just treated. Alongside clinical work, I’ve also been exposed to preventive health, health education, and community outreach. These areas really matter to me because I believe real impact begins outside the hospital, with awareness and early intervention. My approach is always centered around clarity, empathy, and clinical logic—I like to make sure every patient knows exactly what’s going on and why we’re doing what we’re doing. I’ve always felt a pull towards general medicine and internal care, and honestly, I’m still learning every single day—each patient brings a new lesson. Medicine never really sits still, it keeps shifting, and I try to shift with it. Not just in terms of what I know, but also in how I listen and respond. For me, it’s always been about giving real care. Genuine, respectful, and the kind that actually helps a person heal—inside and out.
73 days ago
5

Your history suggests a complex and recurrent sinonasal condition, most consistent with chronic rhinosinusitis with nasal polyps complicated by prior fungal involvement (aspergillus) and possible ongoing environmental exposure. Although the initial surgery and antifungal treatment provided relief, the return of symptoms—fatigue, yellow discharge, and now brown, grainy material with occasional blood—raises concern for persistent inflammation, possible recurrent fungal colonization, or a mixed bacterial–fungal infection rather than a fully invasive fungal disease. The worsening after returning home and your sensitivity to dust or mold strongly point toward environmental triggers contributing to recurrence. The limited response to itraconazole suggests that long-term antifungal therapy alone may not be sufficient, and continuous unsupervised use is not advisable due to potential side effects. Overall, this appears to be a chronic relapsing condition requiring combined management of inflammation, infection, and environmental control rather than relying solely on antifungal medication.

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Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
72 days ago
5

Hello dear See as per clinical history it seems aspergillus infection which causes black mould or rhinosporidiosis It will require extensive medication with combination of bacterial antibiotics and topical antifungal medication I suggest you to please get in person consultation with pulmonary surgeon for better clarity and for safety please donot take any medication without consulting the concerned In addition please take following precautions Avoid dust exposure by wearing mask Avoid cold food intake Tablet montair lc once a day for 3 days Tablet paracetamol 500 mg twice a day 6 hourly a day on fever only Steam twice a day for 15 days Ginger honey combination solution twice a day for 5 days Hopefully you recover soon Regards

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Given the complexity of your condition, it’s crucial to continue managing it carefully even when you don’t have immediate access to medical care. Persistent symptoms like nasal discharge, fatigue, and especially the colored, grainy balls you described can indeed indicate ongoing issues with either fungal or bacterial infections, possibly even inflammation due to regrowth of the polyps.

Firstly, it’s important to ensure your home environment is as free of mold as possible, especially since your past medical history suggests a sensitivity to aspergillus. While comprehensive remediation can be expensive, there are some practical steps you might consider: use dehumidifiers, particularly in damp areas, to reduce moisture levels since mold thrives in humid environments. Regularly clean and replace air filters, and ensure good ventilation in all rooms. If you can identify smaller areas with visible mold, they can be cleaned with a bleach solution or commercial mold remover.

Regarding medication, itraconazole is often used long-term for chronic aspergillosis, but it shouldn’t be used indefinitely without medical supervision due to potential side effects and liver function implications. If it’s not helping and symptoms persist, returning to a healthcare provider when possible is important to reassess your treatment plan. An antifungal susceptibility test might be needed.

Meanwhile, continuing with nasal saline irrigations (like a neti pot) might offer some relief by reducing nasal discharge and clearing out irritants. Ensure the water used is sterile or distilled to prevent infections. Also, nasal corticosteroid sprays as prescribed can help reduce inflammation and polyps regrowth, but these should be monitored by a healthcare provider over the long term.

If you experience severe symptoms like high-grade fever, vision changes, or neurological symptoms, it’s vital to seek urgent medical attention as these could indicate a severe complication. Also, maintaining optimal indoor air quality via air purifiers with HEPA filters may help reduce your exposure to dust and spores, which could alleviate some nasal symptoms.

Ultimately, when you have the means, revisiting an ENT or infectious diseases specialist locally might provide you with an updated picture of your current health status and guide you towards the most appropriate treatment path. For interim, maintaining a symptom diary detailing changes in your symptoms, and any new events can be very useful for future consultations.

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Dr. Arsha K Isac
I am a general dentist with 3+ years of working in real-world setups, and lemme say—every single patient teaches me something diff. It’s not just teeth honestly, it’s people… and how they feel walking into the chair. I try really hard to not make it just a “procedure thing.” I explain stuff in plain words—no confusing dental jargon, just straight talk—coz I feel like when ppl *get* what's going on, they feel safer n that makes all the difference. Worked with all ages—like, little kids who need that gentle nudge about brushing, to older folks who come in with long histories and sometimes just need someone to really sit n listen. It’s weirdly rewarding to see someone walk out lighter, not just 'coz their toothache's gone but coz they felt seen during the whole thing. A lot of ppl come in scared or just unsure, and I honestly take that seriously. I keep the vibe calm. Try to read their mood, don’t rush. I always tell myself—every smile’s got a story, even the broken ones. My thing is: comfort first, then precision. I want the outcome to last, not just look good for a week. Not tryna claim perfection or magic solutions—just consistent, clear, hands-on care where patients feel heard. I think dentistry should *fit* the person, not push them into a box. That's kinda been my philosophy from day one. And yeah, maybe sometimes I overexplain or spend a bit too long checking alignment again but hey, if it means someone eats pain-free or finally smiles wide in pics again? Worth it. Every time.
72 days ago
5

Hello

Given your history of severe sinus disease with Nasal Polyps and prior infection with Aspergillosis, your current symptoms—persistent yellow discharge, grainy debris, occasional blood, and fatigue—are concerning for ongoing sinus inflammation or recurrence, but not necessarily dangerous or spreading to the brain. Recurrence after advanced sinus surgery is unfortunately common, especially when environmental mold exposure continues.

The “brown cheese-like grainy balls” you describe can represent fungal debris, dried mucus, or crusting from chronic sinus inflammation. The fact that symptoms worsen when you return home strongly supports an environmental trigger such as mold, dust, or humidity, rather than medication failure alone. Also, long-term continuous use of Itraconazole is usually not required indefinitely unless a specialist confirms invasive or allergic fungal disease.

What you can do now, even without immediate access to a doctor, is focus on controlling the local sinus environment. Daily saline nasal irrigation (using sterile or boiled-and-cooled water) is one of the most effective low-cost measures to reduce fungal debris and discharge. Continue any prescribed steroid nasal spray if you still have it, as this helps control polyp regrowth and inflammation. Try to reduce indoor mold exposure as much as possible—improving ventilation, using a dehumidifier if available, fixing leaks, and cleaning visible mold with appropriate precautions. Sleeping with the head slightly elevated can reduce nighttime choking on mucus.

It is important to know the warning signs that would require urgent medical care: severe or worsening headache different from usual, high fever, swelling around the eyes, vision changes, confusion, stiff neck, or persistent heavy nosebleeds. Those could indicate complications, which are uncommon but serious.

Overall, your symptoms most likely reflect chronic sinus inflammation with possible fungal colonization, not uncontrolled brain infection. Many people in your situation need periodic treatment cycles rather than permanent antifungal therapy. When financially possible, the most useful next step would be a nasal endoscopy or sinus culture through an ENT specialist to guide treatment precisely.

Take care

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