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Sjogren Symptoms but nothing is detected investigation
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Rheumatic & Autoimmune Conditions
Question #10777
319 days ago
635

Sjogren Symptoms but nothing is detected investigation - #10777

Mrs Shah

49 years old female Dry eyes, dry mouth bluish tongue, body ache and weakness Suffering started since past 2 years Having medicine almost 5 months but no relief Have done all blood work Schimer testing urine tests chest xray etc as per Rheumatologist suggestion Mouth biopsy too Kindly guide

Age: 49
300 INR (~3.53 USD)
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Doctors' responses

Dr. Shayeque Reza
I completed my medical degree in 2023, but honestly, my journey in healthcare started way before that. Since 2018, I’ve been actively involved in clinical practice—getting hands-on exposure across multiple departments like ENT, pediatrics, dermatology, ophthalmology, medicine, and emergency care. One of the most intense and defining phases of my training was working at a District Government Hospital for a full year during the COVID pandemic. It was chaotic, unpredictable, and exhausting—but it also grounded me in real-world medicine like no textbook ever could. Over time, I’ve worked in both OPD and IPD setups, handling everything from mild viral fevers to more stubborn, long-term conditions. These day-to-day experiences really built my base and taught me how to stay calm when things get hectic—and how to adjust fast when plans don’t go as expected. What I’ve learned most is that care isn't only about writing the right medicine. It’s about being fully there, listening properly, and making sure the person feels seen—not just treated. Alongside clinical work, I’ve also been exposed to preventive health, health education, and community outreach. These areas really matter to me because I believe real impact begins outside the hospital, with awareness and early intervention. My approach is always centered around clarity, empathy, and clinical logic—I like to make sure every patient knows exactly what’s going on and why we’re doing what we’re doing. I’ve always felt a pull towards general medicine and internal care, and honestly, I’m still learning every single day—each patient brings a new lesson. Medicine never really sits still, it keeps shifting, and I try to shift with it. Not just in terms of what I know, but also in how I listen and respond. For me, it’s always been about giving real care. Genuine, respectful, and the kind that actually helps a person heal—inside and out.
319 days ago
5

Make sure these were checked: ANA (antinuclear antibody) Anti-Ro/SSA, Anti-La/SSB antibodies RF (Rheumatoid Factor) ESR, CRP (inflammation markers) Lip/Mouth biopsy results, confirm lymphocytic infiltration? Thyroid function tests , Hypothyroidism can mimic some symptoms

Please visit in person consultation near you. Thank you

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Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
319 days ago
5

Hello dear Please be aware See sjogren syndrome is associated with dry eyes and dry mouth characterized by xerostomia It has typically leafless pattern on sialogeam I suggest you to get sialogram repeat along with indirect inflorescence Then kindly share the lab reports with nearby oral pathologist or oral surgeonfor further treatment Regards

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Dr. Neeraj Agarwal
I’m an MBBS graduate with a deep commitment to providing meaningful, patient-first care. My clinical training has given me a solid understanding of how to assess and manage a wide variety of health conditions—both common and complex. But beyond just clinical skills, I’ve always believed that the heart of medicine lies in listening. That’s what I try to bring into every consultation: not just treatment, but genuine attention to the person in front of me. I have gained experience across general medicine, paediatrics, emergency care and preventive health. I have treated patients of different age groups and backgrounds, which has helped shaped a more flexible, to diagnosis and management. Whether someone comes with a new symptom or a routine check-up, I aim to deliver evidence-based treatment, explained clearly and tailored to the lifestyle. I’m especially focused on making care accessible and comfortable. Too often, patients feel rushed or confused when they leave a doctor’s office—I try to do the opposite. Taking time to explain options, risks, or even just what’s going on in simple terms is something I take seriously. Communication, I think, is just as important as any prescription. I actively stay updated with current medical guidelines and research, and I’ve been exploring areas of holistic care and preventive medicine too. The more we can do to catch problems early—or better yet, avoid them—the better the outcome for everyone. I’ve seen how small lifestyle changes, when supported properly, can make a big difference to long-term health. There’s still a lot to learn, of course. I think every good doctor keeps learning. But every patient I see teaches me something new, and I carry those lessons forward—with honesty, empathy, and the intent to keep improving.
319 days ago
5

Share biopsy report and antibody results here – crucial for clarity.

If diagnosis is confirmed Sjögren’s, and there’s no response to symptomatic meds, discuss adding HCQ or low-dose steroids with your rheumatologist.

For ongoing fatigue/pain, rule out fibromyalgia and nutritional deficiencies.

Get a repeat CBC, B12, Iron studies, TSH if not already done.

Symptomatic Relief Artificial tears & ocular lubricants

Pilocarpine or Cevimeline (to stimulate saliva)

Sugar-free lozenges, saliva substitutes

Avoid caffeine, smoking, and alcohol

Autoimmune Control (if positive antibodies/biopsy) Hydroxychloroquine (HCQ)

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Dr. Alan Reji
I'm Dr. Alan Reji, a general dentist with a deep-rooted passion for helping people achieve lasting oral health while making dental visits feel less intimidating. I graduated from Pushpagiri College of Dental Sciences (batch of 2018), and ever since, I've been committed to offering high-quality care that balances both advanced clinical knowledge and genuine compassion for my patients. Starting Dent To Smile here in Palakkad wasn’t just about opening a clinic—it was really about creating a space where people feel relaxed the moment they walk in. Dental care can feel cold or overly clinical, and I’ve always wanted to change that. So I focused on making it warm, easygoing, and centered completely around you. I mix new-age tech with some good old-fashioned values—really listening, explaining stuff without jargon, and making sure you feel involved, not just treated. From regular cleanings to fillings or even cosmetic work, I try my best to keep things smooth and stress-free. No hidden steps. No last-minute surprises. I have a strong interest in patient education and preventive dentistry. I genuinely believe most dental issues can be caught early—or even avoided—when patients are given the right information at the right time. That’s why I take time to talk, not just treat. Helping people understand why something’s happening is as important to me as treating what’s happening. At my practice, I’ve made it a point to stay current with the latest innovations—digital diagnostics, minimally invasive techniques, and smart scheduling that respects people’s time. I also try to make my services accessible and affordable, because good dental care shouldn’t be out of reach for anyone.
316 days ago
5

Your symptoms—dry eyes, dry mouth, bluish tongue, body aches, and long-term weakness—along with no relief from current treatment, could suggest an autoimmune condition like Sjögren’s syndrome, even if tests were inconclusive. Sometimes, these conditions take time to clearly show in lab results. Since you’re under a rheumatologist’s care and not improving, it’s best to get a second opinion from another rheumatologist or an autoimmune specialist for re-evaluation and possibly adjusting the treatment plan.

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Given the challenges you’re experiencing with persistent symptoms that align with Sjogren’s Syndrome but without a definitive diagnosis, it’s crucial to consider both the common and less common factors. Since typical tests like Schirmer’s, blood work for antibodies (SSA/SSB), and even a mouth biopsy haven’t provided clarity, it might be worthwhile to re-evaluate the interpretation of your test results or explore other potential conditions that can mimic these symptoms. Sometimes, early stages or subsets of Sjogren’s might present atypically or might not yet show detectable markers. While Sjogren’s is primarily known for causing dry eyes and mouth, it’s also worth considering other conditions such as fibromyalgia, chronic fatigue syndrome, or even certain vitamin deficiencies like vitamin D or B12 which can sometimes cause overlapping symptoms like body aches and weakness. It may also be valuable to evaluate lifestyle factors that could be contributing, such as stress levels, hydration status, and any medications or supplements you might be taking that could exacerbate dry symptoms. In the meantime, managing symptoms is important: using artificial tears for eyes, saliva substitutes for dry mouth, and possibly working with a nutritionist to ensure a diet that supports overall health. Regular follow-ups with your healthcare provider or seeking a second opinion from a specialist may also lead to new insights. Additionally, keeping a detailed symptom diary can be very helpful for both you and your doctors, documenting any changes or patterns that might otherwise be overlooked in shorter visits.

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