overlap syndromPsc , how to treat - #18590
In patient with 3 years Psc and overlap syndrom , that start treatment with Udca and prednisolone and in 2th yeardswitched to budesonide and now Alk=600 Ast=50 Alt=100 , i want to know prednisolone 10 mg daily is better for maintenance or mycofenolate , to stop the progress,because i dont like mycofenolate for its terrible side effect?
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Doctors’ responses
Hello ,
Continuing low-dose prednisolone is reasonable if tolerated and labs are controlled.
MMF is optional, not mandatory.
Always continue UDCA for PSC.
If your liver enzymes are improving or stable on budesonide, it is reasonable to continue instead of switching to low-dose prednisolone or MMF, especially to avoid systemic steroid side effects.
PLEASE CONSULT YOUR DOCTOR Dont self adjust your regular medication
Thank you
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