What medicines can be given to lower blood urea - #10319
Mother is 77 and has 3.85 creatinine 135 blood urea 8.1 uric acid and around 15 egfr aa per lab report. her hemoglobin is 7.5. what medication can I give to control further damage and lowerthe urea and creatinine levels
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Doctors’ responses
Based on the lab values you’ve shared, your mother seems to have significant renal impairment. The high creatinine and blood urea nitrogen levels, along with a low eGFR, suggest decreased kidney function, which requires a careful approach. While medications like ACE inhibitors or ARBs are often used to protect kidney function long-term and manage hypertension, they should be used with caution and typically under specialist supervision in advanced renal disease. It’s crucial that her condition is managed by a healthcare professional who can assess her risk factors and comorbidities to tailor the treatment. The low hemoglobin level indicates anemia, possibly related to chronic kidney disease, and she might benefit from erythropoiesis-stimulating agents in combination with iron supplementation if iron deficient, but this approach should also be coordinated with her healthcare provider after evaluating her full clinical picture. Medications alone may not effectively lower creatinine and urea, as these levels are often markers of kidney health rather than direct targets for drug therapy; thus, addressing the underlying causes and maintaining optimal fluid, electrolyte balance, and appropriate nutrition is vital. Dietary modifications can play a significant role, including limiting protein, sodium, potassium, and phosphorus intake; however, specific dietary plans should be developed in collaboration with a renal dietitian. Given the complexity of her condition, a nephrologist’s involvement would likely be beneficial for a comprehensive management plan and to evaluate if more intensive treatments, such as dialysis, are needed. It’s essential to avoid any over-the-counter medications or supplements without medical advice due to potential toxicity in renal impairment.
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