Loose diarrhea post colonoscopy damage - #10437
I am a 20-year-old patient experiencing chronic rectal leakage and burning sensation since a colonoscopy performed a few months ago. The leakage is watery or mucous-like, worsens with food or abdominal pressure, and causes severe discomfort. MRI abdomen showed congested mesenteric vessels, but no active inflammation or major pathology. Colonoscopy report did not reveal ulceration or colitis. I have already tried Loperamide, Sucralfate, dietary changes, and probiotics, but there has been no relief. Symptoms continue even without any supplements or triggers. No history of endocrine tumors, infection, or systemic illness. This seems to be a post-procedural secretory gut dysfunction, possibly due to mucosal irritation or neurogenic overactivity. The issue is disabling and affects my daily functioning. Request: I am requesting a trial of Octreotide under supervision to help reduce abnormal intestinal secretions. I am open to other healing agents like L-Glutamine, Sucralfate, or Clonidine, if appropriate. I am willing to follow strict monitoring and local follow-up care as advised. This is not stress-related — I am sincerely seeking a treatment-based solution for persistent gut leakage.
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Doctors’ responses
Hello dear Please be aware I think this is due to side-effects or post operative complications after colonoscopy You can try loperamide once a day and flagyl for immediate relief But better consult the surgeon for clarification Regards
You are not alone or misinterpreting the issue. This is a known but under-recognized complication post-colonoscopy, likely due to disruption of gut neuroendocrine signaling.
A trial of Octreotide + L-glutamine + Clonidine is medically justifiable and should be initiated by a licensed physician under monitoring.
Your description suggests a persistent secretory dysfunction or neurogenic gut overactivity post-colonoscopy, especially with MRI showing mesenteric congestion. Octreotide may indeed help reduce abnormal secretions in such cases, but it requires specialist approval and close monitoring. Consult a gastroenterologist to evaluate suitability for Octreotide, and discuss adjuncts like L-Glutamine, Clonidine, or bile acid binders for symptom control and mucosal healing.
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