Question #10463
12 hours ago
16
I m suffering of I B S as Dr told me. As he suggested, I m taking "Refraximin 200" twice a day since apx last 8 months. If I discontinue in between - #10463
Prakashbhai shah
Is it advisable to take/continue "Refraximin 200" an antibiotic for prolonged periods or life long ? I m afraid of it's side effects, but couldn't stop it as symptoms again develops immediately. Pl explain me deeply. Iff possible, suggest me for alternate remedy having no adverse side effects.
Age: 72
Chronic illnesses: prakashbhaishah53@gmail.com
Indigestion
Stomach ache
Gastric problems
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Doctors’ responses
Rifaximin is not meant for lifelong use.
Cyclic therapy with probiotics and diet correction is safer and more sustainable
If symptoms persist, a gastroenterologist consultation is essential for targeted therapy (e.g., motility agents, bile acid binders, etc.)
Not advisable for lifelong or very prolonged use without re-evaluation
May alter gut microbiota, potentially leading to:
Resistance
Fungal overgrowth
Nutritional imbalance
Risk of relapse after stopping suggests underlying chronic issue (likely SIBO, IBS-D, etc.)
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Rifaximin is NOT safe lifelong — even if "mild," it can cause resistance and gut imbalance
Recurrent symptoms suggest underlying SIBO/IBS or motility issue
Long-term plan should include:
Short bursts of antibiotics (if needed)
Probiotics + gut motility agents
Diet + herbal options
Re-evaluation of cause
Why Symptoms Return When You Stop It?
This usually means there’s an underlying problem that’s not being addressed, such as:
SIBO recurrence due to:
Poor gut motility (e.g., post-infection, diabetes, hypothyroid)
Structural issues (adhesions, diverticula)
Diet triggering regrowth (high fermentable foods)
Alternative
Prokinetics (improve gut movement)-Levosulpiride
Probiotics
Dietary therapy- Low FODMAP diet, lactose-free, avoid fermentable sugars
Herbal antimicrobials (safer for long term) Berberine, Neem, Oregano oil
Stress & gut-brain axis: Yoga, meditation help IBS/SIBO flare-ups
Post-meal walking: Stimulates peristalsis
Spacing meals by 4–5 hrs: Prevents constant fermentation
Sleep and hydration: Influence gut motility
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