I m suffering of I B S as Dr told me. As he suggested, I m taking "Refraximin 200" twice a day since apx last 8 months. If I discontinue in between - #10463
Is it advisable to take/continue "Refraximin 200" an antibiotic for prolonged periods or life long ? I m afraid of it's side effects, but couldn't stop it as symptoms again develops immediately. Pl explain me deeply. Iff possible, suggest me for alternate remedy having no adverse side effects.
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Doctors’ responses
Rifaximin is not meant for lifelong use. Cyclic therapy with probiotics and diet correction is safer and more sustainable If symptoms persist, a gastroenterologist consultation is essential for targeted therapy (e.g., motility agents, bile acid binders, etc.)
Not advisable for lifelong or very prolonged use without re-evaluation May alter gut microbiota, potentially leading to:
Resistance Fungal overgrowth Nutritional imbalance Risk of relapse after stopping suggests underlying chronic issue (likely SIBO, IBS-D, etc.)
Rifaximin is NOT safe lifelong — even if “mild,” it can cause resistance and gut imbalance
Recurrent symptoms suggest underlying SIBO/IBS or motility issue
Long-term plan should include:
Short bursts of antibiotics (if needed) Probiotics + gut motility agents Diet + herbal options Re-evaluation of cause
Why Symptoms Return When You Stop It? This usually means there’s an underlying problem that’s not being addressed, such as:
SIBO recurrence due to: Poor gut motility (e.g., post-infection, diabetes, hypothyroid) Structural issues (adhesions, diverticula) Diet triggering regrowth (high fermentable foods)
Alternative
Prokinetics (improve gut movement)-Levosulpiride Probiotics Dietary therapy- Low FODMAP diet, lactose-free, avoid fermentable sugars Herbal antimicrobials (safer for long term) Berberine, Neem, Oregano oil
Stress & gut-brain axis: Yoga, meditation help IBS/SIBO flare-ups
Post-meal walking: Stimulates peristalsis
Spacing meals by 4–5 hrs: Prevents constant fermentation
Sleep and hydration: Influence gut motility
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