Nerve hypersensitivity after high doses of vit D - #15439

Hello,

🛑Your symptoms are most likely due to how high-dose vitamin D shifted your mineral balance: it raised your calcium and lowered your magnesium, which can make nerves unusually excitable and cause burning sensations, anxiety, feeling on edge, and a fast heartbeat.

These symptoms improved within days of stopping vitamin D strongly supports this.

🛑Meanwhile, your very low iron (despite normal hemoglobin) can explain your remaining issues such as lightheadedness, cold sensitivity, and a rapid heart rate.

Overall, the initial nerve hypersensitivity fits best with the vitamin-D-related calcium/magnesium changes, while your ongoing symptoms align with iron deficiency.

Ok now check please 🛑🛑🛑 Full iron studies (you already have some) but also ferritin Magnesium RBC (more reflective than serum) Calcium, PTH, vitamin D recheck after stopping supplements Consider whether vitamin D dose was too high for your physiology

🛑🛑🛑 Ensure adequate dietary magnesium (nuts, seeds, beans, leafy greens) Avoid high-dose vitamin D until labs are re-evaluated Treat iron deficiency if your doctor confirms it -symptoms often improve within

I trust this helps dear Feel free to reach out again Thank you

Vitamin D at high doses, such as 4000 IU daily, can lead to a range of symptoms, especially if your individual needs or baseline nutrient levels aren’t adequately considered. Your described symptoms might indeed relate to changes in calcium and magnesium levels, as vitamin D helps regulate calcium. An increase in calcium, alongside a decrease in magnesium, can impact nerve function and potentially contribute to what you’re describing as nerve hypersensitivity. With elevated calcium at 2.50 and reduced magnesium, there’s a potential for symptoms like anxiety, irritability, and unusual sensations on the skin, including burning or cold feelings due to nerve irritability. Low magnesium is critical because it’s involved in over 300 enzymatic processes in the body, including nerve and muscle function. Iron deficiency could also be contributing to your symptoms, particularly with lightheadedness and increased heart rate, given that iron is crucial for carrying oxygen in your blood. Your serum iron level of 5.67 does suggest a deficiency despite normal hemoglobin, possibly indicating early stages of iron deficiency anemia – though the body might be compensating to keep hemoglobin within range for now. This deficiency can exacerbate feelings of anxiety and cold sensitivity. It would be prudent to consult your healthcare provider for a comprehensive assessment. They might suggest a temporary pause in high-dose vitamin D and correction of deficiencies, like magnesium and iron. Magnesium can be increased through dietary sources like nuts, seeds, and leafy greens, or supplements at dosages guided by a healthcare professional. Iron levels might improve with dietary intake of iron-rich foods or supplementation under medical supervision. These steps might help rebalance your biochemical environment and reduce symptoms. Meanwhile, if the burning or cold sensations worsen, or are accompanied by significant pain or neurological symptoms, seek prompt medical attention to rule out other causes.

Yes, both low magnesium and low iron can contribute to nerve hypersensitivity, anxiety, palpitations, cold sensitivity, and burning or tingling sensations, and vitamin D supplementation can sometimes worsen magnesium deficiency in susceptible individuals. Your normal hemoglobin with very low serum iron and high TIBC suggests iron deficiency without anemia yet, which can still cause significant symptoms. Please seek evaluation from a physician or neurologist to review your electrolyte levels, iron studies, symptoms, and decide on safe supplementation and treatment.