Nerve hypersensitivity after high doses of vit D - #15439

Hello Mirka By going through your history and evaluation of your health status I must say that - 1) Vitamin D, Magnesium, and Calcium: - High-dose vitamin D can increase calcium absorption, which explains your raised calcium levels. - Vitamin D supplementation can sometimes lower magnesium, especially if your intake isn’t enough to keep up. Magnesium is crucial for nerve function, and low levels can cause symptoms like burning, tingling, and even anxiety. 2) Iron Deficiency: - Your serum iron is quite low, and high TBIC/UIBC means your body is trying to grab more iron, which is a classic sign of iron deficiency—even if your hemoglobin is still normal for now. - Iron deficiency can cause lightheadedness, cold sensitivity, palpitations, and sometimes nerve symptoms. 3) Nerve Hypersensitivity: - yes Both low magnesium and low iron can contribute to nerve hypersensitivity, burning sensations, and mood changes. - The improvement in anxiety after stopping vitamin D suggests your symptoms were likely related to the changes in magnesium and calcium balance.

Suggestions and treatment - 1) avoid over use of vit d3 and take only under doctor prescription 2) For Iron and magnesium consult me in personal for a balanced diet rich in iron and magnesium ( like leafy vegetables, nuts , seafood, etc )

Thank you

Hello dear See after careful evaluation it seems definitely vitamin d toxicity due to overdose It involves dizziness, headache and irritation too. Usually they start at 10,000 Iu but as per clinical history excess calcium causes problem with tremor and palpitations of heart Iam suggesting some tests for better clarification Serum vitamin d Serum calcium ECG Emr Urine calcium Kindly get these tests done for exact clarification and share result with general physician ( medicine) or endocrinologist for further evaluation Please donot take any medication without consulting the concerned physician Regards

low iron AND vitamin-D–induced magnesium depletion can absolutely cause the nerve hypersensitivity, burning/cold sensations, anxiety, and fast heart rate you experienced.

Your symptoms improving after stopping vitamin D strongly supports this.

Hello,

🛑Your symptoms are most likely due to how high-dose vitamin D shifted your mineral balance: it raised your calcium and lowered your magnesium, which can make nerves unusually excitable and cause burning sensations, anxiety, feeling on edge, and a fast heartbeat.

These symptoms improved within days of stopping vitamin D strongly supports this.

🛑Meanwhile, your very low iron (despite normal hemoglobin) can explain your remaining issues such as lightheadedness, cold sensitivity, and a rapid heart rate.

Overall, the initial nerve hypersensitivity fits best with the vitamin-D-related calcium/magnesium changes, while your ongoing symptoms align with iron deficiency.

Ok now check please 🛑🛑🛑 Full iron studies (you already have some) but also ferritin Magnesium RBC (more reflective than serum) Calcium, PTH, vitamin D recheck after stopping supplements Consider whether vitamin D dose was too high for your physiology

🛑🛑🛑 Ensure adequate dietary magnesium (nuts, seeds, beans, leafy greens) Avoid high-dose vitamin D until labs are re-evaluated Treat iron deficiency if your doctor confirms it -symptoms often improve within

I trust this helps dear Feel free to reach out again Thank you

Hi Mirka, your symptoms are most likely from a combination of low magnesium and low iron, both of which can worsen after taking high-dose Vitamin D.

Vitamin D increases calcium and uses up magnesium, which can cause burning/tingling, anxiety, fast heartbeat and cold sensations. Your very low iron levels also add to lightheadedness, cold intolerance and nerve sensitivity.

Next, what should you do is, get a physical consultation done with your nearest Physician, and he/she will prescribe you iron and magnesium supplements according to your requirement. Don’t rely on online consultation for this specific issue.

Feel free to reach out again.

Regards, Dr. Nirav Jain MBBS, DNB D.Fam.Med