Hello Roman By going through your history and evaluation of your health status I must say that it’s better to visit a urologist or medicine doctor in personal with all your report as it seems a long treatment and still not getting benefitted… It basically require more evaluation and more test to confirm the following diagnosis .
Because your symptoms are focusing on fungal infection too so it’s require multiple drugs with proper guidance and evaluation which is not possible without personal .
You will get fine soon
Thank you
Considering the history of brucellosis and treatment with antibiotics like gentamicin, streptomycin, and doxycycline, it’s possible that while the initial infection was controlled, some symptoms may persist due to other underlying issues or damage previously caused by the infection. Brucellosis could potentially lead to complications such as chronic prostatitis or epididymitis, which might explain the persistent genital discharge and sexual dysfunction, even after the brucellosis itself is under control. Additionally, chronic inflammation or persistent bacteria in areas like the prostate can sometimes be resistant to certain antibiotics, which might explain the lack of response to ciprofloxacin and levofloxacin. It’s crucial to re-evaluate the situation with a few steps: First, consult with a urologist or an infectious disease specialist who can assess whether there’s an ongoing, low-level infection or inflammation. They might suggest further diagnostic tests, such as a prostate exam, ultrasound, or even a culture test to search for lingering pathogens or identify possible other infections like chlamydia or gonorrhea, which can also cause similar symptoms. Hormonal evaluation may also be warranted due to sexual dysfunction issues, as brucellosis might affect the endocrine system. Meanwhile, ensure maintaining optimal hygiene, hydration, and avoiding irritants that might exacerbate urinary or genital symptoms. Avoid self-medication with antibiotics, as this can lead to resistance and complicate treatment further. Above all, direct ongoing management with a specialist is key to addressing these symptoms comprehensively.
Hello dear See as per clinical history it seems infection. However it can be additional fungal infection also since it has the probability to invade vagina and other internal organs Also there is history of medication too so I think probably the patient has become resistant too So I suggest you to please get following tests done for confirmation Bacterial culture Fungal culture Antibiotic sensibility PCR must Vaginal swab Rose bengal test Coombs test CBC Pas sensitivity I suggest you to please share the result with general physician ( medicine) for better clarity Please don’t take any medication without consulting the concerned physician since it is chronic and is not getting easily erad ated Hopefully you recover soon Regards
Your symptoms may have causes other than brucellosis and need specialist assessment. Persistent symptoms after repeated antibiotics require urine tests(urine routine and culture), and a detailed urological evaluation(usg whole abdomen). Please do not take any more medicine without a prescription from a qualified doctor. Consult a urologist for proper diagnosis and treatment.
Hello Roman, I understand how frustrating it might be for you. According to what tou explained, it looks like you have something else other than Brucellosis. You need further evaluation.
1. Kindly get these tests done - Urine routine+culture, PCR for STIs, CBC, CRP, HbA1C, Total Testosterone, Free Testosterone, LH, FSH, Prolactin, Ultrasound KUB+Prostate (post void residual). Review with the reports.
2. This is not brucellosis returning. These are common post-infection pelvic issues, especially in males who had severe infection at a young age. Most patients improve significantly with proper evaluation and treatment.
Feel free to reach out again.
Regards, Dr. Nirav Jain MBBS, DNB D.Fam.Med
Investigation
Urine culture PCR for Mycoplasma + Ureaplasma Semen culture Prostate secretion test (EPS – if available) Hormonal Profile Total Testosterone LH, FSH Prolactin TSH (thyroid)
