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Nervous System Disorders
Question #21695
185 days ago
453

So much takleef want true diagnosis

Ilma

Dr I have been diagnosed with triegimmal neuraliga on 12 dec taken oxetol 300mg daily pain relived.but now i am having vertigo so much vomiting loss of appetite i am on anti depressent too fluoxetine 40 bd escitalopram 15mg bd..this vertigo can't made me to stnd straight feeling of vomit vertigo immediately..plse help to understnd what ks actually happening..vomit yesterday I done only watery..

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Doctors' responses

Hello IIma Thank you for sharing these details. You have a history of trigeminal neuralgia (for which you’re taking Oxetol/oxcarbazepine), and you’re also on high doses of antidepressants (fluoxetine and escitalopram). Now you’re experiencing severe vertigo, vomiting, and loss of appetite, and you can’t stand straight due to the vertigo.

Here’s what could be happening: 1. Medication Side Effects:
- Both Oxetol (oxcarbazepine) and your antidepressants can cause dizziness, vertigo, nausea, and vomiting, especially when used together or at higher doses. - Combining fluoxetine and escitalopram (both are SSRIs) is unusual and can increase the risk of side effects, including something called “serotonin syndrome,” which can cause confusion, dizziness, nausea, and more. 2. Electrolyte Imbalance:
- Oxcarbazepine can lower sodium levels in your blood (hyponatremia), which can cause severe dizziness, confusion, and vomiting. 3. Inner Ear or Neurological Issue:
- Less likely, but sometimes vertigo can be due to an inner ear problem or a neurological issue, especially if you have a history of nerve problems.

What you should do: - This situation is serious. You need to see a doctor as soon as possible—preferably today.
- Bring all your medications with you and tell the doctor about your symptoms and the combination of antidepressants. - Do not stop or change your medicines on your own, but do not take any more doses until you speak to your doctor.

Why urgent care is needed:
Severe vertigo, vomiting, and inability to stand can be dangerous and may need blood tests (especially sodium and other electrolytes), medication review, and possibly IV fluids or other treatment.

Thank you and get well soon

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Hello,

Dear you need urgent evaluation 🛑🛑

You may need modification or adjustment in your medication

🛑Your symptoms are NOT from trigeminal neuralgia. They are most likely due to 🛑medicine-induced severe vertigo and vomiting.

Why this is happening: Oxetol (oxcarbazepine) commonly causes vertigo, nausea, vomiting, loss of appetite Taking high-dose antidepressants together (Fluoxetine 40 mg BD + Escitalopram 15 mg BD) greatly worsens dizziness, nausea, imbalance Combination can also cause low sodium (hyponatremia) → severe vertigo, vomiting, weakness

🛑🛑So likely this is Drug-induced vertigo ± hyponatremia

What to do URGENTLY: Get blood test TODAY: Serum sodium, potassium Contact your doctor immediately to: Reduce or stop Oxetol Do NOT take two SSRIs together without specialist supervision

For immediate relief : Ondansetron for vomiting Iv if vomiting continues Betahistine for vertigo

🛑🛑🛑This is a medication reaction, not disease progression. Please act today — this is reversible if treated quickly.

I trust this helps Thank you

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Vertigo and accompanying symptoms like vomiting and loss of appetite can sometimes be side effects of medication, such as the ones you’re taking for trigeminal neuralgia and depression. Oxcarbazepine (Oxetol), can cause dizziness and nausea, especially when you first start or adjust the dose. Some antidepressants also contribute to such symptoms. However, if the vertigo is severe and preventing you from standing or functioning, it’s important to consider other possible causes. Inner ear issues, such as labyrinthitis or vestibular neuritis, can cause vertigo; these often follow infections like colds. Another possibility could be Meniere’s disease, which involves episodes of vertigo, alongside tinnitus and hearing changes. To target the root cause effectively, I’d advise seeing your healthcare provider as soon as possible. They may want to evaluate your current medication regimen, considering potential interactions and side effects. Also, they might perform physical exams or tests, like an MRI or hearing tests, to rule out other causes of vertigo. Until you’re able to see a healthcare provider, try to stay hydrated by taking small sips of water even if you feel nauseous. Avoid sudden head movements and bright lights, as these can sometimes worsen vertigo. It also might be wise to avoid driving or operating machinery until you have better control of your symptoms. If symptoms worsen or you experience any new, concerning symptoms, seek medical attention immediately.

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Hello dear See as per clinical history it seems drug induced side-effects due to multiple medication interaction. Fluoxetine and escitalopram are interacting and causing theses side-effects of vertigo and dizziness. Iam suggesting modification in current medication Please discuss with concerned physician only for modification or replacement of medication. Please not there are less chances of Stroke Brain fog Cardiac arrest So i expect modification in medication will bring improvement in symptoms Regards

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Your current symptoms severe vertigo, repeated vomiting, loss of appetite, inability to stand straight, and watery vomiting are most likely due to medication-related side effects and interaction, rather than trigeminal neuralgia itself.

You are taking: Oxetol (oxcarbazepine) 300 mg Fluoxetine 40 mg twice daily Escitalopram 15 mg twice daily This combination can strongly affect the brain’s balance and nausea centers. What is most likely happening: Oxcarbazepine commonly causes vertigo, dizziness, nausea, and vomiting, especially after initial relief of pain Taking two SSRIs together (fluoxetine + escitalopram) is not recommended and can significantly worsen: Dizziness Nausea and vomiting Loss of appetite Imbalance and weakness Oxcarbazepine can also cause low sodium levels (hyponatremia), which leads to severe vertigo, vomiting, confusion, and inability to stand

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Your severe vertigo, vomiting, and loss of appetite are very likely medication-related, especially from Oxetol (oxcarbazepine) and the high combined doses of fluoxetine + escitalopram, which can cause dizziness, nausea, imbalance, and even electrolyte disturbances. This is not typical trigeminal neuralgia itself and should not be ignored, particularly since you can’t stand straight and are vomiting watery fluid. Please consult a neurologist or psychiatrist urgently (or go to the ER) for medication review, possible dose adjustment, blood tests (especially sodium), and safe symptom control—do not stop or change medicines on your own.

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Hello Ilma, I understand how uncomfortable and frightening this is. Your current symptoms do NOT fit trigeminal neuralgia itself. They strongly suggest a medication-related problem, not a new disease.

This is Not worsening trigeminal neuralgia, Not brain tumor, Not stroke, Not permanent damage.

Contact or visit your treating doctor today, make sure he/she is a certified phychiatrist. He/she will adjust/modify the medicines.

Get done this blood test - Sr. Electrolytes.

Take Tab. Ondansetron 4mg before meals twice a day for vomiting.

Go to ER if: You cannot stand, Continuous vomiting, Confusion, Severe weakness, Palpitations, Fainting.

Feel free to reach out again. Regards, Dr. Nirav Jain MBBS, D.Fam.Medicine

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