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Can I have surgery to remove a neck tumor while taking 4 mg of estrogen daily?
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General Health
Question #29170
13 days ago
49

Can I have surgery to remove a neck tumor while taking 4 mg of estrogen daily? - #29170

Client_8cb7a9

I am a m to f transgender woman they want to remove a tumor in my neck but I am on estrogen 4 mg a day can I have surgery or do I need to stop the estrogen first

How long have you been taking estrogen?:

- Less than 6 months

What type of tumor are you having removed?:

- Malignant

Have you discussed your estrogen therapy with your surgeon?:

- No, I haven't mentioned it

Have you had any complications or side effects from the estrogen?:

- Some mild side effects

When is your surgery scheduled?:

- Within the next week

Have you had any previous surgeries while on hormone therapy?:

- No, this is my first surgery

Are there any other medications you are currently taking?:

- Yes, prescribed medications
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Doctors' responses

Dr. Shayeque Reza
I completed my medical degree in 2023, but honestly, my journey in healthcare started way before that. Since 2018, I’ve been actively involved in clinical practice—getting hands-on exposure across multiple departments like ENT, pediatrics, dermatology, ophthalmology, medicine, and emergency care. One of the most intense and defining phases of my training was working at a District Government Hospital for a full year during the COVID pandemic. It was chaotic, unpredictable, and exhausting—but it also grounded me in real-world medicine like no textbook ever could. Over time, I’ve worked in both OPD and IPD setups, handling everything from mild viral fevers to more stubborn, long-term conditions. These day-to-day experiences really built my base and taught me how to stay calm when things get hectic—and how to adjust fast when plans don’t go as expected. What I’ve learned most is that care isn't only about writing the right medicine. It’s about being fully there, listening properly, and making sure the person feels seen—not just treated. Alongside clinical work, I’ve also been exposed to preventive health, health education, and community outreach. These areas really matter to me because I believe real impact begins outside the hospital, with awareness and early intervention. My approach is always centered around clarity, empathy, and clinical logic—I like to make sure every patient knows exactly what’s going on and why we’re doing what we’re doing. I’ve always felt a pull towards general medicine and internal care, and honestly, I’m still learning every single day—each patient brings a new lesson. Medicine never really sits still, it keeps shifting, and I try to shift with it. Not just in terms of what I know, but also in how I listen and respond. For me, it’s always been about giving real care. Genuine, respectful, and the kind that actually helps a person heal—inside and out.
12 days ago
5

In your situation, having surgery while on estrogen therapy is possible, but it requires careful coordination with your surgical team because estrogen can slightly increase the risk of blood clots (venous thromboembolism) around the time of surgery, especially with anesthesia and reduced mobility. Since your tumor is malignant and surgery is urgent, the priority is not to delay treatment, but many surgeons and anesthesiologists may recommend temporarily stopping estrogen 1–2 weeks before and after surgery to reduce clot risk, depending on your overall health and risk factors. Because you have not yet informed your surgeon, it is very important to tell both your surgeon and anesthesiologist immediately about your estrogen use and any other medications, so they can make a safe, individualized plan for you. Overall, this is a manageable situation, and with proper medical guidance, you can safely proceed with surgery while minimizing risks.

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Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
12 days ago
5

Hello dear Yes it can be continued. As per the recent trend Medication especially for mazir surgery allow intake of estradiol. I suggest you to please mention the current regime to the concerned physician Dose is to be specified and discussed as the current dose is ok . Also in case of Clotting risk Complications Bleeding risk Modification have to be mentioned by anesthesiologist or surgeon Avoid modifying medication of your own Regards

2435 answered questions
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Yes, you can have surgery while on estrogen, but whether you need to stop or adjust your dose first is going to depend on several individual factors. It’s essential to talk with both your surgeon and the doctor overseeing your hormone therapy. There are some considerations regarding how estrogen might affect blood clotting and interactions with anesthesia, so pre-operative assessment will focus on risks versus benefits. If they recommend stopping the estrogen temporarily, it could be because the risk of thromboembolism (blood clots) is higher with estrogen. This typically involves discontinuing it about 4 to 6 weeks before a major surgery, but this varies based on your personal health profile and the specific surgical procedure. Your medical team will evaluate any other medications you’re on, your overall cardiovascular health, and any history of clotting disorders. If they decide you should pause the estrogen, they’ll usually have you resume it after surgery once it’s safe and the risk of clotting decreases, typically when you’re up and moving around regularly during recovery. The goal here is to minimize any surgical risks without compromising your overall well-being or transgender healthcare needs. So, have a detailed conversation with them to discuss your case. They’ll provide the steps tailored specifically for you, ensuring you understand and agree with the surgical plan and any adjustments in your medication regimen.

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Dr. Arsha K Isac
I am a general dentist with 3+ years of working in real-world setups, and lemme say—every single patient teaches me something diff. It’s not just teeth honestly, it’s people… and how they feel walking into the chair. I try really hard to not make it just a “procedure thing.” I explain stuff in plain words—no confusing dental jargon, just straight talk—coz I feel like when ppl *get* what's going on, they feel safer n that makes all the difference. Worked with all ages—like, little kids who need that gentle nudge about brushing, to older folks who come in with long histories and sometimes just need someone to really sit n listen. It’s weirdly rewarding to see someone walk out lighter, not just 'coz their toothache's gone but coz they felt seen during the whole thing. A lot of ppl come in scared or just unsure, and I honestly take that seriously. I keep the vibe calm. Try to read their mood, don’t rush. I always tell myself—every smile’s got a story, even the broken ones. My thing is: comfort first, then precision. I want the outcome to last, not just look good for a week. Not tryna claim perfection or magic solutions—just consistent, clear, hands-on care where patients feel heard. I think dentistry should *fit* the person, not push them into a box. That's kinda been my philosophy from day one. And yeah, maybe sometimes I overexplain or spend a bit too long checking alignment again but hey, if it means someone eats pain-free or finally smiles wide in pics again? Worth it. Every time.
12 days ago
5

Yes, you can usually have surgery to remove a malignant neck tumor while taking estrogen, but the surgical team needs to know you are on hormone therapy because estrogen can slightly increase the risk of blood clots around the time of surgery.

The medication involved is typically Estradiol, and the main concern is clot formation (deep vein thrombosis or pulmonary embolism) during and after major surgery. Because your tumor is malignant, surgery generally should not be delayed, but your doctors may adjust hormone use temporarily to reduce risk.

Whether you need to stop estrogen depends on: • Type and length of surgery • Your personal clot risk (smoking, obesity, prior clots, immobility) • How urgent the cancer surgery is

Common practice is:

• For major cancer surgery, some surgeons recommend stopping estrogen 1–2 weeks before and after surgery if time allows. • For urgent surgery, they may continue estrogen but use blood clot prevention measures (compression stockings, blood thinners, early walking).

What you should do now (important): Tell your surgeon and anesthesiologist as soon as possible that you are taking estrogen 4 mg daily. This is essential information for safe planning. Do not stop the medication on your own unless your surgical team instructs you.

Bottom line: • Surgery is still possible and usually proceeds. • Estrogen may or may not need to be paused briefly.The decision is individualized based on risk and urgency of the malignant tumor removal.

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