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What to do for severe nerve pain in thigh that isn't improving with treatment?
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Nervous System Disorders
Question #30759
54 days ago
157

What to do for severe nerve pain in thigh that isn't improving with treatment?

Sazzad Hossain

Hope you are doing well. I am Noyon, 28 years old, Male, Weight 68 kg. I am contacting you as I am suffering from severe nerve pain and need your kind advice. *Brief History:* I have been suffering from lower back pain radiating to my left/right thigh for 8 days. The pain is sharp, burning type, and increases while sleeping or resting. *Treatment Taken:* I consulted Dr. Md. Masud Rana, Assistant Professor, Medicine, MMCH on 15th June 2026. He prescribed the following medicines which I am taking regularly: 1. Mirotin 5 mg (Levocetirizine Dihydrochloride 5 mg) – 0+0+1 2. Lino M 2.5/500 mg (Linagliptin 2.5 mg + Metformin Hydrochloride 500 mg) – 1+0+1 3. Maxpro MUPS 20 mg (Esomeprazole 20 mg) – 1+0+0 4. Neucos B (Vitamin B1 + Vitamin B6 + Vitamin B12) – 1+0+1 5. Sentrx 0.5 mg (Clonazepam 0.5 mg) – 0+0+1 6. Napsod 550 mg (Naproxen Sodium 550 mg) – 1+0+1 7. Maxolax 5 mg (Bisacodyl 5 mg) – 0+0+1 8. Felbo gel - Apply 3-4 times daily *Investigations Done on 15/06/2026:* 1. HbA1c: 7.1% 2. Random Blood Sugar: 8.6 mmol/L 3. TSH: 1.59 mIU/L 4. Lipid Profile: Total Cholesterol 218, LDL 148, HDL 35, Triglyceride 173 [Borderline/High] 5. CRP: <6 mg/L 6. Xray LS Spine B/L: lumbar spondylosis *Current Complaint:* Despite taking all medicines regularly for 4 days, my thigh nerve pain is not reducing. I have severe burning/shooting pain in my thigh which is disturbing my daily work and sleep at night. Napsod and Felbo gel are giving very little relief. *Request:* Sir, I would be very grateful if you kindly review my case and advise me: 1. Should I continue the same treatment? 2. Do I need any change in medicine or dose, especially for nerve pain? 3. Should I come to Dhaka for physical examination and further tests like MRI LS Spine/Nerve conduction study? note : I took aceclofenac for reducing pain during paining, but that medicine didt not properly worked. i need a pain killer Sir. All my prescription and test reports are attached for your kind review. I will be waiting for your valuable advice. Sorry to bother you. With due respect, Noyon

How would you describe the intensity of your nerve pain?:

- Moderate — affects activities

Have you experienced any other symptoms along with the nerve pain?:

- Numbness or tingling

How has your pain changed since starting the current medications?:

- Slightly improved

What activities make your pain worse?:

- No specific activity triggers

Have you had any previous treatments for this condition?:

- No, this is my first treatment

How is your sleep quality affected by the pain?:

- Frequently disturbed

Do you have a history of any chronic conditions?:

- Diabetes
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Doctors' responses

Hello dear As per clinical history it seems chances of Sciatica Bursitis Hamstring injury It causes Limited arm movement Significant pain Swelling Pseudoparalysis It requires following tests for confirmation. Please share the result with orthopedic surgeon in person for better clarity and for safety please donot take any medication without consulting the concerned physician Esr CBC Mri Arthrography Shoulder USG There may be requirement of Rest Physiotherapy Medication like Diclofenac sodium gel topical application Crave bandage application Limited stretching Selective cox -2 inhibitors like Refecoxicib See I have suggested methods as per My clinical experience I suggest you to please have in person consultation at Dhaka for better clarity Hopefully you recover soon Regards

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Given your description of severe nerve pain in the thigh, despite taking your prescribed medications, it sounds like a more focused investigation might be warranted. Let’s go through what could be beneficial in your situation. First, continuing with your current treatment could be helpful in managing underlying conditions like high blood sugar and anxiety, which can exacerbate nerve pain. However, given the lack of relief from pain-specific medications, you might need adjustments in your treatment plan.

A change in pain management could be appropriate, possibly switching from Naproxen to another type of non-steroidal anti-inflammatory drug (NSAID) like ibuprofen, or even considering medications specifically aimed at nerve pain like gabapentin or pregabalin, which are sometimes more effective for neuropathic pain. This decision should be made alongside your healthcare provider.

Regarding diagnostics, since your pain is severe and persistent, further evaluation with an MRI of the lumbar spine and possibly a nerve conduction study would be wise, particularly to rule out any serious nerve compression or radiculopathy that might need more direct interventions such as physical therapy or, in some cases, surgical consultation.

If access to such imaging and tests is more viable in Dhaka, it could be worthwhile making the trip. Given the severity of your symptoms, this should be prioritized sooner rather than later, particularly if you’re seeing no improvement.

Additionally, non-medication strategies can sometimes play a role in pain management. Gentle physical therapy and sometimes even acupuncture can provide relief, but these should be employed cautiously and ideally under professional guidance to avoid exacerbating the pain.

Keep in mind that high blood sugar levels, as indicated by your HbA1c, may also contribute to nerve pain, so ensuring these are managed effectively is crucial. Monitoring your dietary intake and working closely with your doctor to manage your glucose levels could have indirect beneficial effects on your nerve pain.

Please arrange a timely follow-up with a healthcare provider to reassess your treatment plan and discuss adjustment options.

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