Morphea morphea morphea morphea - #11506
I have morphea on neck can u suggest any cream best one i already using tofacitinib but noresponse is there any update about morphea and and recent developmentsof morphea cream for results sugyany cream
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Doctors’ responses
For morphea, particularly if tofacitinib isn’t yielding the desired outcomes, considering topical therapy options is certainly worthwhile. While tofacitinib is an oral treatment sometimes used off-label for this condition, evidence for topical treatments remains a predominant focus, especially for localized lesions. One of the mainstays of treatment includes high-potency topical corticosteroids, like clobetasol propionate. They can reduce inflammation and slow skin thickening. Apply it carefully to the affected area, generally once or twice daily, as advised by a healthcare professional. However, prolonged use requires attention due to potential side effects like skin thinning. Another topical option is calcipotriene, a vitamin D analog, which may be used alone or with corticosteroids and helps to effectuate more normalization of the skin. Both options have been fairly documented for their usefulness in combating localized morphea. More recent advances involve topical tacrolimus, an immunomodulator, which has shown promise in some cases by targeting the immune response without the risks of skin thinning associated with steroids. It’s often applied twice daily, effective particularly in softer or early lesions. Assessing combinations with phototherapy, like UVA1, might also enhance outcomes, but requires access to specialized equipment and supervision. It’s critical to follow-up closely with your dermatologist to tailor treatments effectively, as individual response can vary. Keep abreast of research developments, ensuring work-up to rule out deeper or more systemic involvement. In severe or resistant cases, systemic therapies or newer biologics could be considered, but these typically involve more extensive evaluation. Always discuss options and new developments with your healthcare provider, ass they can guide the approach based on the specific pattern and severity of the condition you’re experiencing.
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