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Is it normal to feel tired and sick after taking magnesium glycinate for the first time?
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General Health
Question #29473
45 days ago
99

Is it normal to feel tired and sick after taking magnesium glycinate for the first time? - #29473

Client_e68656

Took 100mg of magnesium glycinate last night. Produced 1300ml of urine overnight. To day I feel tired, groggy, sick. Is this normal? This was the first time I took it.

How long after taking magnesium glycinate did you start feeling these symptoms?:

- Next day

Have you experienced any other symptoms besides tiredness and grogginess?:

- Headache

How would you describe your typical energy levels before taking magnesium?:

- Occasionally tired

Have you taken any other supplements or medications recently?:

- Yes, prescription medications

How much water do you usually drink in a day?:

- 1-2 liters

Did you have any food or drink with the magnesium glycinate?:

- No, took it on an empty stomach

Have you had any previous reactions to magnesium or other supplements?:

- No, never had issues
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Doctors' responses

It isn’t typical to experience tiredness, grogginess, or feeling sick from taking magnesium glycinate, especially from just a 100mg dose. Magnesium glycinate is often well-tolerated and is generally used to supplement magnesium levels or address deficiencies without many side effects at regular doses. However, everyone can react differently. Your symptoms might be related to several factors, including dehydration from increased urine output since this could lead to electrolyte imbalances. If you aren’t used to high levels of fluid loss, then replacing lost electrolytes and fluids is important. Drinking water and ensuring a balanced diet with essential electrolytes like potassium and sodium could help alleviate these symptoms. It’s worth considering if the supplement might have interacted with other medications or if you ate or drank anything unusual recently. If your symptoms persist or worsen, it would be wise to consult a healthcare provider to rule out other possible causes such as underlying health concerns, which could be unrelated to the supplement. Prioritize medical attention if you notice severe or sudden changes in your health, especially if you develop symptoms like dizziness, confusion, or continuous vomiting. In the meantime, pausing this supplement until you get professional advice could be reasonable to avoid potential exacerbation of your symptoms.

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Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
42 days ago
5

Hello dear Yes this dose can be taken However the symptoms mentioned here related to Dehydration Electrolytes deficiencies Weakness Sodium retention I Suggest you to please get in person consultation with general physician medicine for better clarity Regards

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