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What could be causing my brother's recurring fever and weakness since November 2025?
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Infectious Illnesses
Question #29523
137 days ago
355

What could be causing my brother's recurring fever and weakness since November 2025?

Client_355203

Hi, my brother has reccuring fever from nov 2025. Like he gets the fever for5-6 days, then completely normal, then next month again. So recently he was again admitted 26th March, then by 30th discharged, on 8th April this time fever came early but it was not high, it was fluctuating in btwn 99-100.4, then consulted a doctor, for now fever isn't there, but this time he is feeling little weak and inactive

How often does your brother experience these fever episodes?:

- Once a month

Has he had any other symptoms along with the fever?:

- Nothing else

How would you describe the severity of the fever when it occurs?:

- Mild (99-100°F)

Has he undergone any tests or treatments during his hospital stays?:

- Imaging studies (like X-ray or CT scan)

Has there been any recent travel or exposure to infections?:

- Not sure

How is his appetite and energy level when he is not experiencing fever?:

- Normal appetite and energy

Does he have any known medical conditions or take any medications?:

- No known conditions
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Doctors' responses

Hello

Recurring fever every month since November 2025, lasting about 5–6 days and then resolving, is called recurrent or periodic fever. The pattern you described suggests an underlying cause that needs systematic evaluation, even if the fever is only mild (99–100.4°F) and he feels normal between episodes.

Common causes doctors consider include infections that relapse or persist at low levels, inflammatory or immune conditions, and less commonly blood disorders. In many parts of India, the most frequent possibilities are: • Tuberculosis (can be mild and intermittent) • Malaria • Typhoid fever • Brucellosis • Systemic lupus erythematosus • Blood-related conditions such as anemia or, rarely, leukemia

The fact that he was admitted in late March and discharged after a few days suggests doctors did not find a critical emergency cause at that time, but recurrent monthly fever for 5+ months still needs a structured workup, especially now that he is feeling weak and less active.

What should be done next is a focused medical evaluation rather than repeated short treatments. Useful tests usually include: • Complete blood count (CBC) with peripheral smear • ESR and CRP (inflammation markers) • Malaria test (rapid test or smear) • Typhoid test (blood culture or Typhi test) • Chest X-ray (if not already done) • Urine test • Liver and kidney function tests • Tuberculosis screening (Mantoux or IGRA) If fevers continue, doctors may also consider ultrasound abdomen or more specialized tests.

He should seek medical review urgently (within days) if any of these appear: • Weight loss • Night sweats • Persistent fatigue or weakness • Swollen lymph nodes • Fever lasting longer than usual • Appetite loss • New cough or abdominal pain

Take care

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Hello dear See it seems either incomplete infection elemination or recurring infection Probably below infection can reoccur Tuberculosis Typhoid Viral fever STD I suggest you to please following tests done for confirmation Please share the result with general physician medicine for better clarity CBC Esr Culture Afb Serum TSH Widal test Typhus test Antibody titre Hopefully you recover soon Regards

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Recurring fevers, especially when they present in patterns, can stem from a range of underlying causes, so it’s crucial to get a thorough evaluation. The causes could be infeccious in nature, such as recurring or chronic infections like tuberculosis or certain viral infections that can have periodic flare-ups. Non-infectious causes could include autoimmune conditions, like systemic lupus erythematosus, or even malignancies like leukemia or lymphoma, which can be associated with cyclical fevers. Given that he’s also experiencing weakness, this symptom aligns with several of these conditions. It’s important that your brother undergoes further diagnostic work. Basic investigations like complete blood count, blood cultures during fever spikes, and inflammatory markers (CRP, ESR) can offer initial insights. Imaging studies like a chest X-ray or CT scans might be warranted depending on findings. Sometimes doctors will employ specific blood tests to rule out particular diseases - for instance, specific antibody tests if there’s suspicion of autoimmune diseases. Be actively engaged with the healthcare provider about any new or worsening symptoms as these might offer crucial leads. Though it’s good the fever has currently abated, tracking his symptoms, such as the exact pattern of fevers and any additional new sx, will assist the medical team in finding the correct diagnosis. Prompt evaluation is necessary as some underlying causes of recurrent fevers can be serious and require proactive management. Make sure he follows up with his doctor who might consider referring him to a specialist like an infectious disease expert or a hematologist if necessary.

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