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What is the best treatment for premature ejaculation in a 38-year-old man who has tried multiple therapies without success?
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Sexual Health & Wellness
Question #29644
18 days ago
72

What is the best treatment for premature ejaculation in a 38-year-old man who has tried multiple therapies without success? - #29644

Client_85ab83

"دكتور، أنا عمري 38 سنة، وأعاني من سرعة القذف منذ المراهقة تقريبًا. جرّبت المخدرات الموضعية، وتمارين كيغل، وطريقة التوقف والبدء، وكذلك جرّبت الدابوكسيتين، لكن دون تحسن كافٍ. هذا الموضوع سبب لي قلقًا وخوفًا من الزواج، وأريد تقييمًا كاملًا لمعرفة السبب وخطة علاج فعالة تناسب حالتي."

How long have you been experiencing premature ejaculation?:

- Since adolescence

How would you rate the severity of your condition?:

- Severe — significantly affects relationships

Have you noticed any specific situations that trigger your symptoms?:

- No specific triggers

How is your overall emotional and mental health?:

- Moderate anxiety affecting daily life

Have you discussed your condition with a healthcare professional before?:

- No, this is the first time

What is your current lifestyle like in terms of diet and exercise?:

- Not sure

Have you experienced any other sexual health issues?:

- No, just premature ejaculation
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Doctors' responses

Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
18 days ago
5

Hello dear Please be aware See following medications can be taken in case if preventive therapy is not successful

Sildenafil empty stomach to be taken Tadalafil Accordingly if recommended by gynacolologist Vardenafil Levitra or Staxyn in case if allergic to Sildenafil Avanafil accordingly if recommended In addition please take the following precautions Avoid heavy meals and alcohol Take ashwagandha or triphala once a day for 2 months Do meditation Do physical exercises atleast for half an hour Especially kegel exercises Take shilajeet for 1 month once a day In case of no improvement in 1 month, kindly consult gynaecologist for further clarification Hopefully you recover soon Regards

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Dr. Arsha K Isac
I am a general dentist with 3+ years of working in real-world setups, and lemme say—every single patient teaches me something diff. It’s not just teeth honestly, it’s people… and how they feel walking into the chair. I try really hard to not make it just a “procedure thing.” I explain stuff in plain words—no confusing dental jargon, just straight talk—coz I feel like when ppl *get* what's going on, they feel safer n that makes all the difference. Worked with all ages—like, little kids who need that gentle nudge about brushing, to older folks who come in with long histories and sometimes just need someone to really sit n listen. It’s weirdly rewarding to see someone walk out lighter, not just 'coz their toothache's gone but coz they felt seen during the whole thing. A lot of ppl come in scared or just unsure, and I honestly take that seriously. I keep the vibe calm. Try to read their mood, don’t rush. I always tell myself—every smile’s got a story, even the broken ones. My thing is: comfort first, then precision. I want the outcome to last, not just look good for a week. Not tryna claim perfection or magic solutions—just consistent, clear, hands-on care where patients feel heard. I think dentistry should *fit* the person, not push them into a box. That's kinda been my philosophy from day one. And yeah, maybe sometimes I overexplain or spend a bit too long checking alignment again but hey, if it means someone eats pain-free or finally smiles wide in pics again? Worth it. Every time.
17 days ago
5

Hello

When premature ejaculation has been present since adolescence and happens every time, even after trying topical anesthetics, Kegel exercises, stop-start techniques, and Dapoxetine, the condition is usually what doctors call lifelong primary premature ejaculation, medically known as Premature Ejaculation.

The key point is that this pattern is rarely due to a structural problem or “damage.” It is most often related to a combination of high penile sensitivity, fast ejaculatory reflex pathways, and performance anxiety, especially when the issue started early in life. The fact that you also report low libido and anxiety about marriage suggests there may be a hormonal or psychological component that deserves proper evaluation rather than repeating the same treatments.

At this stage, the best next step is a full assessment, not just another trial of the same methods. Doctors typically check three areas. First is hormones, particularly testosterone and thyroid function, because conditions like Hypogonadism or Hyperthyroidism can worsen ejaculation control and reduce libido. Second is screening for chronic prostate or pelvic inflammation such as Chronic Prostatitis, which can increase sensitivity. Third is evaluating anxiety and sexual confidence, since long-standing worry can keep the nervous system in a hyper-aroused state.

In men who do not respond to single treatments, the most effective approach is usually combination therapy, tailored to the individual. This may include a different daily medication from the same family as dapoxetine (rather than on-demand dosing), sometimes combined with topical therapy or behavioral therapy under guidance. When low libido is present, correcting any hormonal imbalance can significantly improve both desire and ejaculation control. Many men who felt “untreatable” respond once the plan is personalized instead of relying on one method alone.

Most importantly, lifelong premature ejaculation does not prevent marriage, sexual satisfaction, or fertility. It is one of the most treatable sexual health conditions when approached systematically, and improvement is common even after years of symptoms.

A practical next step would be to request these baseline tests from a clinician: morning testosterone, thyroid function (TSH), fasting glucose, and possibly a semen or prostate evaluation if symptoms suggest inflammation. That evaluation usually clarifies the cause and opens more targeted treatment options.

Take care

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عند التعامل مع مشكلة مثل سرعة القذف التي لم تتحسن بالطرق التقليدية، من المهم النظر في مجموعة عوامل يمكن أن تسهم في هذه الحالة، مثل الأسباب النفسية أو القضايا الصحية الأخرى. قد تحتاج إلى تقييم متكامل ليتسنى الكشف عن أي عوامل غير مدروسة قد تكون السبب. بينما قمت بالفعل بتجربة بعض العلاجات الشائعة مثل المخدرات الموضعية والدابوكسيتين، يوصى بالتفكير في استشارة معالج متخصص في الصحة الجنسية أو طبيب مسالك بولية للقيام بفحص شامل. قد يتضمن هذا الفحص اختبار التحاليل اللازمة لتقييم الهرمونات مثل التستوستيرون أو البحث عن أي أعراض أخرى قد تشير إلى مشكلة طبية. يمكن أن يساعد العلاج السلوكي، الذي يركز على تغيير السلوكيات الجنسية والتقنيات التي يتم استخدامها أثناء النشاط الجنسي، في العديد من الحالات. بالإضافة، هناك أدوية أخرى مثل مثبطات إعادة امتصاص السيروتونين الانتقائية (SSRIs) التي يمكن أن تحدث فرقًا. هذه الأدوية يمكن أن تمد وقت استجابة القذف عند استخدامها بجرعات منخفضة. بالإضافة إلى ذلك، يمكن الطرح لمواضيع مثل إدارة التوتر النفسي والقلق، حيث يمكن أن يكون للضغوط النفسية أثر كبير على هذا الأمر. من المهم المتابعة المستمرة مع المتخصصين للوصول إلى العلاج الأكثر فعالية والمناسب لحالتك الفردية.

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