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Can I undergo a second IVF after high liver enzymes during my first pregnancy?
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Gynecology & Pregnancy Care
Question #29870
34 days ago
103

Can I undergo a second IVF after high liver enzymes during my first pregnancy? - #29870

Client_94ef61

Am 32 years had my ivf at 27, twin pregnancy, during my first ivf in had severe liver enzymes which were so high doctor suggested elective c section, at 34 weeks please doctors can I go for second ivf wil it affect my liver again or should I forget about ivf and go for adoption instead

What were the specific liver enzyme levels during your first pregnancy?:

- Severely elevated

Did you experience any symptoms related to liver issues during your first pregnancy?:

- Yes, mild symptoms

Have you undergone any follow-up tests for your liver since your first pregnancy?:

- Yes, normal results

Have you made any lifestyle changes since your first pregnancy?:

- Yes, improved diet and exercise

What is your current overall health status?:

- Good with minor issues

Have you discussed your concerns with a fertility specialist?:

- Yes, in detail

What is your main concern about undergoing another IVF cycle?:

- Risk to liver health
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Doctors' responses

Dr. Bharat Joshi
I’m a periodontist and academician with a strong clinical and teaching background. Over the last 4 years and 8 months, I’ve been actively involved in dental education, guiding students at multiple levels including dental hygienist, BDS, and MDS programs. Currently, I serve as a Reader at MMCDSR in Ambala, Haryana—a role that allows me to merge my academic passion with hands-on experience. Clinically, I’ve been practicing dentistry for the past 12 years. From routine procedures like scaling and root planing to more advanced cases involving grafts, biopsies, and implant surgeries. Honestly, I still find joy in doing a simple RCT when it’s needed. It’s not just about the procedure but making sure the patient feels comfortable and safe. Academically, I have 26 research publications to my credit. I’m on the editorial boards of the Archives of Dental Research and Journal of Dental Research and Oral Health, and I’ve spent a lot of time reviewing manuscripts—from case reports to meta-analyses and even book reviews. I was honored to receive the “Best Editor” award by Innovative Publications, and Athena Publications recognized me as an “excellent reviewer,” which honestly came as a bit of a surprise! In 2025, I had the opportunity to present a guest lecture in Italy on traumatic oral lesions. Sharing my work and learning from peers globally has been incredibly fulfilling. Outside academics and clinics, I’ve also worked in the pharmaceutical sector as a Drug Safety Associate for about 3 years, focusing on pharmacovigilance. That role really sharpened my attention to detail and deepened my understanding of drug interactions and adverse effects. My goal is to keep learning, and give every patient and student my absolute best.
33 days ago
5

Hello dear See presence of increased hepatic enzymes donot limit your reproductive ability But yes they are mandatory to know the exact health There are some late pregnancy complications Intrahepatic Cholestasis HELLP Syndrome Preeclampsia Acute Fatty Liver So i suggest you to please get in person consultation with gynaecologist fir better clarity Regards

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The key factor here is understanding what caused the elevated liver enzymes during your first pregnancy to assess if it can happen again. Such elevations can be associated with conditions like HELLP syndrome, preeclampsia, or obstetric cholestasis during pregnancy. Each of these has different implications and risks in a subsequent pregnancy. Before considering another IVF cycle or any conception method for that matter, it’s essential to have a comprehensive evaluation by your healthcare provider. A liver function test and possibly other tests to assess your current liver health would be crucial. If the cause was something like HELLP syndrome, the risk of recurrence in a subsequent pregnancy can be significant, and close monitoring would be essential.

Discussing your particular case with a specialist, ideally an obstetrician with experience in high-risk pregnancies, would be beneficial. They can help tailor the unique risks of another IVF cycle and pregnancy against your past health history. Monitoring and preventive strategies can be planned to lessen the chances of liver issues reoccurring. In addition, a team approach involving a hepatologist might also provide a broader perspective on how your liver might react to pregnancy-related changes. It’s not a straightforward decision like choosing between IVF or adoption because your overall health and risks should steer this choice. It’s feasible to proceed safely with another pregnancy through careful monitoring and support but requires clarity on previous issues.

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