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Seeking Medication Recommendations for Depression and Sexual Side Effects
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Mental & Emotional Health
Question #27023
135 days ago
299

Seeking Medication Recommendations for Depression and Sexual Side Effects

Client_7f6068

I thank all the doctors here who have taken time to reply to my first inquiry earlier. I'm planning on seeing a psychiatrist again to help with my low mood and depression. I already saw one and was given trimipramine that helped me a lot with my anger crisis but didn't help at all lifting my mood from the total depression controlling my life. trimipramine have sexual side effects that are still lingering after years from finishing the course. I didn't do testosterone levels but there rest of my blood work is okay (normal cbc, thyroid function, fasting glucose, kidneyfunction, heart health ...etc)... I am asking for recommendations from you of medication that I can ask the psychiatrist for that should help lift my depression and mood and maybe reverse the sexual side effects of trimipramine if you could recommend anything. Thanks and I am grateful in advance for your support

How long have you been experiencing low mood and depression?:

- More than 6 months

Have you experienced any specific triggers for your low mood?:

- No specific triggers

What other treatments have you tried for your depression?:

- Therapy (e.g., CBT)
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Doctors' responses

Hello

Ask your psychiatrist about: • Bupropion → lifts mood, very low sexual side effects, may improve sexual function • Vortioxetine → effective for depression with low sexual side effects • Mirtazapine → good for mood + sleep, minimal sexual effects

If another antidepressant is used, adding low-dose bupropion can reduce sexual side effects.

Also consider testosterone check and hormone review.

Review of current stress, sleep, and overall health — improving depression itself often improves sexual function.

You can say: “I need an antidepressant that lifts mood but minimizes sexual side effects — could we consider bupropion, vortioxetine, or an add-on strategy?”

I trust this helps Thank you Take care

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Hello dear See improvement will occur but it will require time Iam suggesting some methods for improvement Please follow them for atleast two months Do physical exercise atleast half an hour daily for 5 months Do meditation Take good balanced diet for good health Engage in social media Indulge in hobbies like reading and writing Avoid overthinking Avoid junk food and alcohol/ smoking Set your goals for every day Hopefully improvement will occur In case of no improvement in 2 month consult psychiatrist in person for better clarity Regards

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While it’s good that you’re planning to speak with a psychiatrist, it’s important to tailor any medication to your specific need and symptoms, considering the complete context of your health. In terms of managing depression while minimizing sexual side effects, there are a few avenues you might consider discussing with your psychiatrist. SSRIs, like escitalopram or sertraline, are commonly used, but they can also occasionally affect sexual function. If they haven’t been effective or tolerated before, you could consider SNRIs like venlafaxine, which some people tolerate better in terms of sexual health. Bupropion is another option that is often noted for having a lower risk of sexual side effects and may even improve them. It works differently than SSRIs and SNRIs and could be beneficial for mood and energy improvement. Since you’ve had a history with trimipramine, which is a tricyclic antidepressant, it’s good you’ve noticed what didn’t work well and to see new options. Detailed conversation with your psychiatrist is key here to balance efficacy, side effect profile and any personal history with medication. Also, think about discussing lifestyle elements that help support medication like regular exercise, fair sleeping patterns, and nutritional considerations. Monitoring testosterone could be reasonable as part of investigating sexual health concerns, given your history. Finally, adjusting or changing medications should always be done with guidance from your healthcare provider to account for unique responses and potential interactions.

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