Seeking Medication Recommendations for Depression and Sexual Side Effects - #27023
I thank all the doctors here who have taken time to reply to my first inquiry earlier. I'm planning on seeing a psychiatrist again to help with my low mood and depression. I already saw one and was given trimipramine that helped me a lot with my anger crisis but didn't help at all lifting my mood from the total depression controlling my life. trimipramine have sexual side effects that are still lingering after years from finishing the course. I didn't do testosterone levels but there rest of my blood work is okay (normal cbc, thyroid function, fasting glucose, kidneyfunction, heart health ...etc)... I am asking for recommendations from you of medication that I can ask the psychiatrist for that should help lift my depression and mood and maybe reverse the sexual side effects of trimipramine if you could recommend anything. Thanks and I am grateful in advance for your support
How long have you been experiencing low mood and depression?:
- More than 6 monthsHave you experienced any specific triggers for your low mood?:
- No specific triggersWhat other treatments have you tried for your depression?:
- Therapy (e.g., CBT)100% Anonymously
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Doctors' responses
Hello
Ask your psychiatrist about: • Bupropion → lifts mood, very low sexual side effects, may improve sexual function • Vortioxetine → effective for depression with low sexual side effects • Mirtazapine → good for mood + sleep, minimal sexual effects
If another antidepressant is used, adding low-dose bupropion can reduce sexual side effects.
Also consider testosterone check and hormone review.
Review of current stress, sleep, and overall health — improving depression itself often improves sexual function.
You can say: “I need an antidepressant that lifts mood but minimizes sexual side effects — could we consider bupropion, vortioxetine, or an add-on strategy?”
I trust this helps Thank you Take care
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